Impaired astrocyte function can result in decreased elimination of extracellular glutamate, leading to a reduced seizure threshold and an imbalance between neuronal excitation and inhibition (Bialer & White, 2010)
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Cell 188 , 20432062 (2025)
Examples include: Organ transplant recipients Certain autoimmune conditions Long-term immunosuppressive therapy Understanding risk factors helps explain why regular skin examinations are so important
Similarly, patients with cobalt hypersensitivity should avoid this medication, as methylcobalamin contains cobalt as part of its molecular structure